Cannabinoid hyperemesis syndrome: Care instructions

While pesticides can lead to adverse chs syndrome health problems, this is likely not the cause of CHS. The exact cause of CHS isn’t fully understood, but researchers believe it involves the body’s natural cannabinoid system. Cannabis interacts with receptors in the brain and digestive tract, and in cases of cannabis hyperemesis syndrome, these receptors may become overstimulated. This overstimulation can disrupt normal digestive functions, causing symptoms like nausea, vomiting, and stomach pain.

• And a 2022 Canadian study found that ER visits for CHS-related problems had increased 13-fold between 2014 and 2021.
• If that were not sufficiently ominous, observed mutations on the ATP-binding cassette transporter (ABCA1) could increase risks of future abnormal protein deposition in the brain, dementia, coronary artery disease and Type II diabetes (Feher et al., 2018).
• Future research, both clinical and pre-clinical, should continue to investigate the underlying mechanism and pre-disposing factors of CHS, to further understand the consequences of high-dose cannabinoid use and dysregulation of the endocannabinoid system.
• Trying to power through your daily responsibilities can feel almost impossible.
• Certainly, recognition of the disorder has increased since its initial description, which has paralleled a marked escalation of THC concentrations in cannabis, along with more broad accessibility to those products, as well as synthetic alternatives.

Cannabinoid hyperemesis syndrome: Care instructions

This article will explain the causes of CHS and the available treatment options. If you suspect CHS or need guidance, feel free to contact us for support and treatment options. “It may be that the cannabinoid is only sort of one aspect of the way the patient is hurting that needs to be addressed to really get Drug rehabilitation them to heal,” he said.

Prevalence of CHS

• They’ll also examine your abdomen and may order tests to rule out other causes of vomiting.
• Cannabinoid hyperemesis syndrome (CHS) is a condition in which a patient experiences cyclical nausea, vomiting, and abdominal pain after using cannabis.
• Over time, these receptors may become overactive, leading to the severe nausea and vomiting experienced by people with CHS.
• The Rome IV criteria provide some objectivity to help with the diagnosis by placing CHS under the heading of functional gut-brain disorders, and consider it as a variant of CVS (Table 2).
• One possible explanation for this is called “gate control theory,” which postulates that to some extent, the brain can regulate how much pain it perceives.

This increased blood flow to the skin and peripheral tissues may help shift blood volume away from the gastrointestinal tract, potentially alleviating nausea and vomiting symptoms by reducing visceral hypersensitivity and enhancing overall comfort levels. In shedding light on the complexities of CHS, healthcare providers are empowered to navigate the diagnostic challenges, forge accurate identifications, and deliver tailored management strategies that uphold the well-being and health outcomes of patients grappling with this enigmatic syndrome. One study found that 32.9% of self-reported frequent marijuana users who came to an emergency department for care met the criteria for CHS. With the widespread use, increased potency and legalization of marijuana in multiple states in the U.S., CHS may be becoming increasingly common. While marijuana seems to bring on nausea in the stomach, in the brain it usually has opposite effect. When cannabinoids bind with brain receptors, they tend to prevent nausea and vomiting.

How Cannabis Hyperemesis Syndrome Makes You Vomit — a Lot

Sometimes it’s the same person returning after a second or third bout with the condition. “One of the reasons why we are interested in this mycotoxin is because we think that it might have an association with cannabis hyperemesis,” Leung said, referring to a syndrome that can cause vomiting fits known to affect some long-term cannabis users. Cannabinoid hyperemesis syndrome (CHS) is a somewhat rare problem that involves severe bouts of vomiting. As more states make recreational use of cannabis legal, it is thought that this problem will become more common.

• This word is a combination of “screaming” and “vomiting.” You’re in so much pain that you’re screaming while you’re vomiting.
• This can be especially hard — and maybe seem unfair to some — considering the condition doesn’t affect all long-term cannabis users.
• Although selective breeding has produced plants with 93% of total cannabinoid content as THCV (de Meijer and Hammond, 2016), residual THC content remains the rule, as THCA synthase produces both the pentyl and propyl molecules in the cannabis plant.
• If you start using again, there’s a good chance you’ll cycle back into the prodromal and hyperemetic phases.
• While conventional antiemetic medications like serotonin 5-HT3 receptor antagonists and dopamine antagonists can be prescribed to manage nausea and vomiting in CHS patients, their efficacy in CHS cases is limited.

They can begin as mild problems that make you feel sick in the morning. She is a communications expert working with Dr. Green Relief, specializing in creating engaging content that promotes holistic health and well-being. Olivia is interested in the intersection of mental health, mindfulness, and alternative therapies, which she explores through her writing. Her work aims to educate and inspire readers to adopt healthier, more balanced lifestyles.With a background in communications and a dedication to personal growth, Olivia brings a unique perspective to her articles, blending scientific insights with practical advice for everyday life. Treating Cannabinoid Hyperemesis Syndrome (CHS) focuses on relieving symptoms and preventing their return.